Melanoma is the deadliest type of skin cancer. It begins in the pigment cells of the skin called melanocytes and spreads through the blood and lymphatic system to distant organs, such as the lungs, liver, and brain.

Melanocytes are cells that produce melanin to protect the skin from sun’s ultraviolet (UV) radiation. A Moles or Nevi is formed when these cells cluster together in the skin throughout childhood or adolescence. Melanoma develops when abnormal melanocytes proliferate (rapidly multiply and increase in number) uncontrollably. About 33 percent of all melanomas arise from preexisting moles, although they can appear anywhere on the skin.

Melanoma normally starts in the skin (cutaneous melanoma), but cancer can occur in the eye (ocular melanoma) or the moist tissue that lines specific regions of your body (mucosal melanoma). It can happen wherever melanocytes exist even if they are not exposed to sunlight. Primary melanoma is the location of a melanoma’s formation.

Clinical features / Symptoms of Skin cancer

• The most common clinical presentation is an ulcer that nerve heals, sometimes healing takes place with scabbing and later it breaks down and forms ulcer again.  The ulcer has raised and beaded edge; indurations may be present and bleeds on touch. The base can be subcutaneous fat or deeper structures like muscle or bone depending upon invasion.
• It can also present as a painless, firm, nodule, which is pigmented with fine blood vessels on its surface.
• It can present as a nodular ulcerative form.
• Rarely, it can be cystic variety which does not show fluctuation.
• Field fire rodent ulcer is a rapidly growing rodent ulcer with destruction and disfigurement of the facial skin. It has an advancing edge with healed central scar.

The types of skin cancer includes

• Basal cell carcinoma.
• Squamous cell carcinoma.
• Malignant melanoma.

Basal cell carcinoma

The most common types are basal cell carcinoma and Squamous cell carcinoma. Among skin cancers about 70% are basal cell carcinoma, 20% are Squamous cell carcinoma and 5% are melanocarcinoma. Other rare skin cancers are sebaceous carcinomas, dermoid cystic carcinomas etc.

Basal cell carcinoma is the most common skin cancer; generally, it is a slow-growing neoplasm which can present as an ulcer of many years’ duration. In some cases, it can present as locally penetrating, ulcerative and destructive lesion. It arises from basal cell of the pilosebaceous adnexa and occurs only on the skin.

Common sites – inner canthus of the eye, outer canthus of the eye, eyelids, bridge of the nose, around nasolabial fold. These sites are the areas where the tears roll down. Hence it is also called tear cancer.

Squamous cell skin cancer

Typically, it is an ulcerative or cauliflower like lesion:

• Edge is everted and indurated.
• Base is indurated and it may be subcutaneous tissue, muscle or bone.
• Floor contains cancerous tissue which looks like granulation tissue. It is pale, friable, bleeds easily on touch.
• Surrounding area is also indurated.
• Mobility is usually restricted due to Infiltration of underlying structures.
• Regional lymph nodes like inguinal lymph nodes can get enlarged when Squamous cell carcinoma affects lower limb or abdominal wall.

Malignant melanoma

It is a malignant skin cancer arising from pigment- forming cells which are derived from the neural crest. Melanocyte and Melano blasts convert dihydroxyphenylalanine into melanin. This is called positive DOPA reaction. It is potentially curable skin cancer in early stages. If left untreated or if not treated properly, it disseminates rapidly, showers the body with tumor emboli and offers a very painful death.

Common sites of malignant melanoma

• Head and neck 20-30%
• Lower extremity 20-30%
• Trunk 20-30%
• Remaining cases occur in upper extremities, genitalia, choroid of the eye, etc.

There are basic four types of melanoma

Three of them begin in situ means they occupy only the top layers of the skin — and sometimes become invasive; the fourth one is invasive from the start. Invasive melanomas are more serious, as they have penetrated deeper into the skin and may have spread to other areas of the body.

(1) Superficial spreading melanoma:

It is the most common type of melanoma. It accounts for about 70 percent of all cases. This type is mostly seen in young people. This melanoma grows along the top layer of the skin and sometimes penetrating skin more deeply. The first sign of appearance of this is irregular borders and is somewhat asymmetrical in form. The color varies, and areas become tan, brown, black, red, blue or white. This type of melanoma can occur in a previously benign mole. The melanoma can be found almost anywhere on the body but is most likely to occur on the trunk in men, the legs in women, and the upper back in both sexes.

(2) Lentigo maligna:

It is similar to the superficial spreading type, as it also remains close to the skin surface, and usually appears as a flat or mildly elevated mottled tan, brown or dark brown discoloration. This type is found most often in the elder peoples, arising on chronically sun-exposed, damaged skin on the face, ears, arms and upper trunk.

(3) Acral lentiginous melanoma:

This type is also spreading superficially before penetrating more deeply. It is quite different from the others, as it usually appears as a black or brown discoloration under the nails or on the soles of the feet or palms of the hands. This type is sometimes found on dark-skinned people.

(4) Nodular melanoma:

It is usually invasive at the time it is first diagnosed. The malignancy is recognized when it becomes a bump. It is usually black in color, but occasionally is blue, gray, white, brown, tan, red or skin tone. The most frequent locations are the trunk, legs, and arms, as well as the scalp in men. It is mostly seen in elderly people. This is the most aggressive of the melanomas and is accounts for about 10 to 15 percent of cases.

Basic Pathology of Melanoma: – Melanoma stages are depending upon the size or thickness of the tumor and also whether spreads to the lymph nodes or other organs. Depending upon TNM classification, stages of Melanoma are as follows:

Stage “O” melanoma:

Stage 0 melanoma means the cancer cells are confined to the epidermis and have not spread deeply. At this stage, the cancer is usually handled by surgery alone.

Stage I melanoma:

Stage I melanoma means the cancer cells have grown deeper into the skin but have not spread to the distant lymph nodes or other parts of the body. This is further classified into: –

• Stage IA: In this stage, the cancer is very small, less than 1 mm in diameter, and does not appear ulcerated. It is not spreading rapidly to other organs.
• Stage IB: In this stage, cancer is either very small, less than 1 mm in diameter, but it is ulcerated or spreading rapidly to other organs, OR the cancer is between 1-2 mm deep without any sign of ulceration.

Stage II melanoma:

Stage II melanoma means the cancer cells have grown deeper into the skin, or have more complications, but have not spread to the lymph nodes or beyond that. This type is further sub-divided into: –

• Stage IIA: in this stage, cancer cells have grown 1-2 mm deep into the skin, and the tumor appears ulcerated.
• Stage IIB: The cancer is 2-4 mm thick with ulceration.
• Stage IIC: The cancer is more than 4 mm thick, and it is ulcerated.

Stage III melanoma:

Stage III melanoma means the melanoma cancer cells have spread to nearby lymph nodes, but not to the distant organs. They are further divided into: –

• Stage IIIA: The cancer can be any size, without ulceration, but a small number of cancer cells which can only be seen under a microscope have been found in 1-3 nearby lymph nodes.
• Stage IIIB: Melanomas at this stage can be any size but they are ulcerated with cancer cells in 1-3 lymph nodes that can only be seen under a microscope.
• Stage IIIC: Melanomas at this stage can be any thickness. If it is ulcerated, either 1-3 nearby lymph nodes are enlarged OR cancer cells can be found in the nearby skin or lymphatic channels.

Stage IV melanoma:

Stage IV melanoma means the cancer cells have spread beyond the skin and regional lymph nodes to distant organs such as the liver, lungs or brain, or distant lymph nodes and areas of the skin.

Clinical Presentation of melanoma: -The “ABCD” rule is another way to recognize abnormal growths that may be melanoma skin cancer:

Signs and Symptoms of Melanoma

The signs and symptoms of Melanoma are:

• A change in an existing mole.
• The development of a new pigmented or unusual-looking growth on skin.
• Sores that do not heal.
• Pigment, redness or swelling those spreads outside the border of a spot to the surrounding skin.
• Itchiness, tenderness or pain.
• Changes in texture or scales, oozing or bleeding from an existing mole.

Normal Moles or Nevi

• Normal moles are symmetrical; if you draw a line across the center, the color, thickness, and form of both sides would match.
• The edges are clean and smooth.
• Usually, normal moles have a brown hue, which is continuous throughout.
• Moles are formed during childhood or adolescence and do not change their characteristics, such as size, shape, and color once completely formed.
• Moles are typically less than 6 mm in diameter.
• A bigger size mole may not necessarily cause melanoma, but it is necessary to pay attention to notice any possible changes.
• Moles are often flat you can run your finger over them and not notice them.

Cancerous Moles or Nevi (melanoma)

• Asymmetry: These moles are asymmetrical, the two sides of the mole do not match with shape, color, size, or thickness.
• Border: Melanoma borders are often irregular with scalloped or notched margins.
• Color: A cancerous mole is not uniform in color or contains shades of tan, brown, black, blue, white, or red.
• Diameter: Melanoma spreads and tends to get bigger, having a diameter of more than 6 mm.
• Evolving: Melanomas may begin flat but rise as they expand. It is most certainly abnormal if you can feel it.

Other signs of melanoma include:

• Non-Healing sores.
• Bleeding from border.
• Formation of scales, oozing, or bleeding from the surface.
• Itching.
• Pain.
• Inflammation and swelling around it.

Diagnosis

Wedge biopsy from the edge of the ulcer is the main investigation in case of basal cell carcinoma.

Melanoma may become fatal in less than six weeks if left untreated. It spreads to other regions of the body if not treated. Melanoma may develop on skin that has not been exposed to the sun regularly.

The basic allopathic treatment for melanoma is surgery, especially when detected in the early stages. However, your specific treatment will be determined by your circumstances. If melanoma is not detected until the advanced stage, treatment focuses on limiting the development of the disease and alleviating symptoms.

This generally includes drugs that target genetic abnormalities in the melanoma, such as BRAF inhibitors, or strengthen the body’s immune responses to the tumor (immunotherapy).

Melanoma may reoccur if you have had it previously. The risk of recurrence increases if the cancer was more advanced or extensive.

If patient is at high risk of recurrence, doctor may recommend regular monitoring. Patient will be briefed on how to evaluate the skin and lymph nodes for melanoma.

Homeopathic treatment of Moles or Nevi and other skin cancers

According to WHO the allopathic treatments are generally considered ineffective for metastatic melanoma leading frequently to the development of chronic side effects, toxicity in patients and sometimes to therapeutic failures. Therefore, the use of complementary and alternative medicines (CAM) as integrative therapy by cancer patients, in parallel with anticancer treatments prescribed by oncologists, has increased considerably over the past 30 years. Homeopathy is part of these CAM. Developed in the 18^th century by German physician Samuel Hahnemann, it is based on two principles: the Law of Similars (“similia similibus curantur; let likes be cured by likes”).

The effect of homeopathy has already been recognized, especially for improving the cancer patients’ quality of life, and many studies have only begun to demonstrate the effect of some homeopathic dilution in cancer cell lines, in vitro. For instance, Lycopodium clavatum 5 Centesimal Hahnemannian (CH) and 15CH have the capacities to induce apoptosis in HeLa cancer cells, and the “Canova method” composed of several homeopathic dilutions, can stimulate the immune system by activating macrophages.

Furthermore, a recent study shows that Ruta graveolens 30CH is able to decrease cell viability and cell migration, by increasing apoptosis of the human colon cancer.

Considering all these facts and despite a context that tends to question the existence of any effect related to homeopathic treatments, we have decided to evaluate the impact of low homeopathic dilutions of phenacetine in vitro on melanoma cell lines. The chemical basis of this homeopathic dilution is phenacetine, an aromatic organic compound known as a drug with analgesic and antipyretic properties, comparable to paracetamol.

Until 1983, phenacetine was used over the counter in remedies for pain and fever and also in rheumatoid arthritis, highly diluted can produce an effective reduction of their usual toxic aspect in vitro/in vivo and increase beneficial application.

Based on this knowledge, the present study will describe for the first time the effects of low-diluted Phenacetinum (Phenacetinum 4CH – 1 × 10⁻⁸ _M), on cancer cell migration in vitro for murine cutaneous melanoma cell lines. Indeed, the combination of different original methodologies makes it possible for Phenacetinum 4CH to disrupt lipid organization at the plasma membrane, affecting underlying cytoskeleton performance and thereby, dispersed cell migration.

Berberis Vulgaris

Flat warts. Itching, burning and smarting; worse, scratching; better, cold applications. Small pustules over whole body. Eczema of anus and hands. Circumscribed pigmentation following eczematous inflammation.

 Fagonia Cretica Q (Dhamasa)

Anti-cancerous properties and is known to be good against breast cancer, liver cancer, anal cancer, and lung cancer.  Antidiabetic, anti-leishmanial, antipyretic, anti-inflammatory, laxative, gastroprotective, hepatoprotective, cardioprotective and has good antioxidant effects.

Graphites for Moles or Nevi

Like all the carbons, this remedy is an anti-psoric of great power, but especially active in patients who are rather stout, of fair complexion, with tendency to skin affections and constipation, fat, chilly, and costive. Rough, hard, persistent dryness of portions of skin unaffected by eczema. Early stage of keloid and fibroma. Pimples and acne. Eruptions, oozing out a sticky exudation. Rawness in bends of limbs, groins, neck, behind ears.

Unhealthy skin: every little injury suppurates. Skin cancers. Ulcers discharging a glutinous fluid, thin and sticky. Swelling and induration of glands. Gouty nodosities. Cracks in nipples, mouth, between toes, anus. Phlegmonous erysipelas of face; burning and stinging pain. Swelling of feet. Red spots on the skin, like fleabites. Erysipelatous inflammations. Vesicular erysipelas, like zona, Itching of the varices on the lower limbs.

Itching-stinging on the surface of a mole. Eruptions oozing out a thick honey-like fluid. Tetters, and other humid or scabby eruptions, sometimes with secretion of corrosive serum, or with itching in the evening, and at night. Eruption of pimples and nodules (principally under hair and on covered parts) which itch very much. Swelling and induration of the glands. Encysted tumors. Corrosive nodules. Excoriation of the skin (in the bends of the limbs, groins, neck, behind the ears), especially in children. Every injury tending to ulceration. Proud flesh, and fetid pus, in ulcers, with tearing pains, burning, and shooting. Scrofulous and syphilitic ulcers. Burning pain in an old cicatrix. Deformity and thickness of the nails.

Thuja Occidentalis for Moles or Nevi

Polypi, tubercles, warts epithelioma, naevi, carbuncles; ulcers, especially in ano-genital region. Freckles and blotches. Perspiration sweetish, and strong. Dry skin, with brown spots. Zona; herpetic eruptions. Tearing pains in glands. Glandular enlargement. Nails crippled; brittle and soft. Eruptions only on covered parts; worse after scratching. Very sensitive to touch. Coldness of one side. Sarcoma; polypi. Brown spots on hands and arms.

Nitric Acid

Warts, large jagged; bleed on washing. Ulcers bleed easily, sensitive; splinter-like pains; zigzag, irregular edges; base looks like raw flesh. Exuberant granulations. Black pores on face, papules worse on forehead. Dryness of the skin. Itching nettle-rash, also on face, and especially in open air. Blackness of pores. Brown sphacelus. Reddish-brown spots and deep-colored ephelis on skin. Copper or violet-colored spots. Itching tetters. Pimples, or exanthema in general; stinging exanthema.

Pain from chilblains and corns on feet. In a moderately cold temperature limbs become as if frozen, inflamed, and itching, and skin cracks. Large furunculi. Mercurial ulcers. Carious ulcers. Complaints, Wounds and ulcers, with lancinations as by splinters, or with burning pains especially when they are touched, and which bleed easily. Inflammation and painful sensitiveness of the bones. Caries. Inflammation, swelling, and suppuration of the glands. Ulceration of the bones. Rachitis. Ulcers with sinuous, sanguineous, and corrosive suppuration. Pains in old scars on a change of weather. Condylomas moist, like cauliflower, hard, rhagade, or in thin pedicles. Tightness of skin. Swelling of glands. Warts. Wens.

Lycopodium Clavatum

Ulcerates. Abscesses beneath skin; worse warm applications. Hives; worse, warmth. Violent itching; fissured eruptions. Acne. Chronic eczema associated with urinary, gastric and hepatic disorders, bleeds easily. Skin becomes thick and indurated. Varicose veins, naevi, erectile tumors. Brown spots, freckles worse on left side of face and nose. Dry, shrunken, especially palms; hair becomes prematurely gray. Dropsies. Offensive secretions; viscid and offensive perspiration, especially of feet and axilla. Psoriasis. Carcinoma.

Causticum

The skin of a Causticum person is of a dirty white sallow, with warts, especially on the face. Emaciation due to disease, worry, etc, and of long standing. Burning, rawness, and soreness are characteristic.  Soreness in folds of skin, back of ears, between thighs. Warts large, jagged, bleeding easily, on tips of fingers and nose. Old burns that do not get well, and ill effects from burns. Pains of burns. Cicatrices freshen up; old injuries reopen. Skin prone to intertrigo during dentition.

Carbo Animalis

Ulceration and decomposition. All its secretions are offensive. Causes local congestions without heat. Spongy ulcers, copper-colored eruption. Acne rosacea. Chilblains, worse in evening, in bed and from cold. Verruca on hands and face of old people, with bluish color of extremities. Glands indurated, swollen, painful, in neck, axillae, groin, mammae; pains lancinating, cutting, burning (Con; Merc iod flav). Burning, rawness and fissures; moisture. Bubo.

Antimuonium Crudum for Moles or Nevi

Eczema with gastric derangements. Pimples, vesicles, and pustules. Sensitive to cold bathing. Thick, hard, honey-colored scabs. Urticaria; measle-like eruption. Itching when warm in bed. Dry skin. Warts. Dry gangrene. Scaly, pustular eruption with burning and itching, worse at night. Itching in the neck, chest, back and limbs. Eruptions. Miliary eruptions and nettle-rash. Tumors and blisters, as if from the stings of insects. Measles-like eruption. Eruptions, similar to chickenpox, with shooting pain on pressure.

Thick, hard scabs, often honey-yellow, here and there a crack oozing a green sanious fluid, burning as if immersed in hot embers. Urticaria white, with red areolae, which itch fearfully. Pustules with yellowish or brown scurf. Freckles. Hepatic spots. Deep spongy ulcers with gastric ulcers. Fistulous ulcers. Horn-like excrescences and disposition to abnormal organizations of the skin. Corns and callous excrescences on the feet. Nails discolored and deformed. Red and hot swellings. Degeneration of the skin. Fungus of the joints.

Sabina

Fig-warts, with intolerable itching and burning. Exuberant granulations. Warts. Black pores in skin.

Mezereum for Moles or Nevi

Eczema; intolerable itching; chilliness with pruritus; worse in bed. Ulcers itch and burn, surrounded by vesicles and shining, fiery-red areola. Zona, with burning pain. Bones, especially long bones, inflamed and swollen; caries, exostosis; pain worse night, touch, damp weather (Merc; Syph). Eruptions ulcerate and form thick scabs under purulent matter exudes.

Crusta lactea. Ear, affections of; sensitive to air. Erythema. Exostoses. Eyes, affections of. Glands enlarged. Gleet. Gonorrhea. Hematuria. Hernia. Herpes zoster. Impetigo. Irritation. Leucorrhea. Mercury, effects of. Neuralgia. Osteoma. Pediculosis. Pityriasis. Prolapsus ani. Pruritus senilis. Rheumatism. Scrofula. Syphilis. Teeth, affections of. Tinea capitis. Tinea versicolor. Tongue, affections of; swelling of. Ulcers. Vaccination.

Skin. Sensitive to touch. General desquamation of skin of body; usual liver spots on chest and arms become dark and desquamate. Red rash, itching violently; Cutaneous ulcers form over bony protuberances. Ulcers with thick, whitish, yellow scabs, under which thick, yellow pus collects. Skin covered with elevated white scabs. Itching, especially at night (when in bed), more violent and painful (and changed to burning) after scratching the parts, and sometimes with swelling of the part that has been scratched.

Miliary eruptions, sometimes chronic. Furunculi. Inflamed ulcers, with burning and shooting, or with gnawing pain of excoriation. Inflammation and swelling of the bones, rachitis, caries. Ulcers: with an areola, sensitive and easily bleeding when removing the linen, which sticks, painful at night, the pus tends to form an adherent scab, under which a quantity of pus collects, burning and stinging with inflammation. Vesicles around the ulcers, itching violently and burning, like fire. Suppuration after inflammation.

Chrysarobinum

Acts as a powerful irritant of the skin and used successfully in skin diseases especially in ringworm, psoriasis, herpes tonsurans acne rosacea. Vesicular or squamous lesions, associated with foul smelling discharge and crust formation, tending to become confluent and to give the appearance of a single crust covering the entire area (Bernstein). Violent itching, thighs, legs and ears. Dry, scaly eruption, especially around eyes and ears, scabs with pus underneath.

Calcarea Carbonicum for Moles or Nevi

Skin unhealthy; readily ulcerating; flaccid. Small wounds do not heal readily. Glands swollen. Nettle rash; better in cold air. Warts on face and hands. Petechial eruptions. Chilblains. Boils. Flaccidity of the skin. Visible quivering of the skin from head to foot, followed by giddiness. Burning, smarting, itching. Ephelis. Nettle Rash, mostly disappearing in the fresh air. Eruption of lenticular red and raised spots, with great heat, much thirst, and want of appetite. Skin hot and dry during motion. Skin of the body rough, dry, and as if covered with a kind of miliary eruption.

Furfuraceous coating of the skin; burning; chapped. Humid, scabby eruptions and tetters, or in form of clusters, with burning pains. Itching pemphigus over the whole body. Skin excoriated in several places. Skin unhealthy; every injury tends to ulceration; even small wounds suppurate and do not heal. Ulcers deep; fistulous; carious. Ulcers with too little pus. Erysipelatous inflammations. Furunculi. Warts. Corns, with pain as of excoriation, and burning. Polypus (nose, ear, uterus). Encysted tumors, which are renewed and suppurate every month. Bloatedness. Swelling and induration of the glands, with or without pain. Varices. Arthritic nodosities. Swelling; softening; curvature of; stinging in; caries and distortion of the bones. Ulceration of the bones. Panaris. Flaws in the fingers.

Sulphur

Dry, scaly, unhealthy; every little injury suppurates. Freckles. Itching, burning; worse scratching and washing. Pimply eruption, pustules, rhagades, hangnails. Excoriation, especially in folds (Lyc). Feeling of a band around bones. Skin affections after local medication. Pruritus, especially from warmth, is evening, often recurs in springtime, in damp weather.

Rhus Toxicodendron for Moles or Nevi

Skin: Red, swollen; itching intense. Vesicles, herpes; urticaria; pemphigus; erysipelas; vesicular suppurative forms. Glands swollen. Cellulitis. Burning eczematous eruptions with tendency to scale formation. Vesicular erysipelas where the vesicles are large. Exanthema on face in general on chin, face, cheeks, mouth, nose, forehead, causing much burning itching. Pustulous chilblains. Exanthema with swelling; blotches; like milk-crust; moist; like nettle-rash; blue with erysipelas; scurfy; tensive or tight feeling in; pock-shaped; black; purulent; zona or shingles; petechiae; prickling; tickling; blisters which will sometimes spread up the limb, and are sometimes circular in form, spreading with a red edge in the advance, which gradually turns to a blister, the red border still keeping in advance.

Stinging and tingling on skin, burning after scratching. Humidity of skin. Hardness of skin with thickening. Swelling (hard) of affected parts. Gangrenous ulcers resulting from small vesicles, with violent fever. Petechiae, with great weakness, amounting to entire prostration. Black pustules. Herpes, sometimes alternately with asthmatic sufferings and dysenteric looseness. Warts, especially on hands and fingers; large jagged, often pedunculated, exuding moisture and bleeding readily. Rhagades on hands. Panaritium. Tingling or shooting or else burning smarting in ulcers. Chilblains. Corns on feet, with burning sensation, and pain as of excoriation.

Kreosotum for Moles or Nevi

Clinical: Acne. Amenorrhea. Cancer. Carbuncle. Change of life. Cholera infantum. Coccygodynia. Congenital syphilis. Constipation. Consumption. Dentition. Diarrhea. Ear, affections of. Enuresis. Epithelioma. Eructation. Eruptions. Flushing. Gastro Malacia. Glossitis. Hemorrhages. Hemorrhagic diathesis. Herpes. Hysterical vomiting. Irritation. Leucorrhea. Lip, epithelioma of. Lupus. Menstruation, disorders of. Neuralgia. Ovary, affections of. Prostate, irritation of. Pregnancy, vomiting of. Pustules. Rheumatism. Seasickness. Stomach, affections of. Syphilis. Syphilitic deafness. Teeth, caries of. Toothache. Ulcers. Urine, incontinence of. Uterus, affections of. Vomiting. Whooping-cough. Yawning.

Skin -Soft, unnatural feel of skin, with pegged teeth. Violent itching all over body, esp. towards evening, and with burning sensation in arms and legs, after scratching. Burning itching at night, and heat over whole body. Nettle-rash. Eruption, like bug-bites, with violent itching especially in evening. Large, greasy-looking, pox-shaped pustules over whole body. Mealy and pustular, dry or humid tetters (on backs of hands and fingers, in palms, on ears, elbows, knuckles, and malleoli), with violent itching in almost every part of body.

Crotalus Horridus

Swelling and discoloration, skin tense and shows every tint of color, with excruciating pain. Vesication. Sallow. Yellow color of the whole body. Great sensitiveness of skin of right half of body. Purpura hemorrhagic. Hemorrhage from every part of body. Bloody sweat. Chilblains, felons. Dissecting wounds. Pustular eruptions. Insect stings. Post-vaccination eruptions. Bad effects of vaccination. Lymphangitis and septicemia. Boils, carbuncles, and eruptions are surrounded by purplish, mottled skin and oedema. Anthrax. Sore sensation relieved by pressure.

Lachesis for Moles or Nevi

kin: Hot perspiration, bluish, purplish appearance. Boils, carbuncles, ulcers, with bluish, purple surroundings. Dark blisters. Bed-sores, with black edges. Blue-black swellings. Pyemia; dissecting wounds. Purpura, with intense prostration. Senile erysipelas. Wens. Cellulitis. Varicose ulcers. Ecchymosis: wounds and ulcers bleed readily and copiously (small wounds bleed a good deal; ulcers bleed readily; cicatrices bleed readily; pain in old cicatrices), wounds bleeding a great while; skin very hard to heal, masses of blood pass through the pores.

Varicose swellings. Dropsical swelling over whole body. Hard and pale tumefaction. Skin yellow, green, lead-colored, or bluish-red or blackish, chiefly round the wounds and ulcers. Yellow, red, copper-colored spots. Pale, livid spots, with fainting fits. Dry, miliary itch, with eruption of large vesicles of a yellow or of a bluish black color, with swelling of parts affected, and pains which drive to despair. Miliary eruption, which subsequently resembles nettle-rash, scarlatina, or morbilli. Erysipelas and vesicular eruptions with a red crown. Excoriated places, on touching which a burning pain is felt.

Rupia and other skin affections, with angioleucitis (Cooper). Ulcers, surrounded by pimples, vesicles, and other small ulcers (on a purple skin). Ulcers with great sensitiveness to touch, uneven bottom, ichorous, offensive discharge when touched, esp. around the lower extremities. Gangrenous ulcers. Gangrenous blisters. Superficial ulcers, foul at bottom, with a red crown.

Cancerous ulceration (of wounds), or putrefaction of the flesh, which becomes detached from the bones, and falls off piecemeal. Gangrenous wounds, with inflammatory fever, weak, quick, and intermittent pulse, fainting nausea, spasmodic and bilious vomiting, convulsions, and cold sweats. Papulae, warts, hard swellings. Panaris. Red and itching lumps and tuberosities. Carbuncles, with copper-colored surroundings and many smaller boils around them. Flat exanthemata which do not fill up; pustulous exanthemata; spongy excrescences.

Phosphorus

Wounds bleed very much, even if small; they heal and break out again. Jaundice. Little ulcer outside of large ones. Petechiae. Ecchymosis. Purpura hemorrhage. Scurvy. Fungus haematodes and excrescences.

 Silicea

Felons, abscesses, boils, old fistulous ulcers. Delicate, pale, waxy. Cracks at end of fingers. Painless swelling of glands. Rose-colored blotches. Scars suddenly become painful. Pus offensive. Promotes expulsion of foreign bodies from tissues. Every little injury suppurates. Long lasting suppuration and fistulous tracts. Dry fingertips. Eruptions itch only in daytime and evening. Crippled nails. Indurated tumors. Abscesses of joints. After impure vaccination. Bursa. Lepra, nodes, and coppery spots. Keloid growths.

Carbo Vegetables for Moles or Nevi

Skin: Blue, cold ecchymosed. Marbled with venous over distension. Itching; worse on evening, when warm in bed. Moist skin; hot perspiration; senile gangrene beginning in toes; bed sores; bleed easily. Falling out of hair, from a general weakened condition. Indolent ulcers, burning pain. Ichorous, offensive discharge; tendency to gangrene of the margins. Purpura. Varicose ulcers, carbuncles. Sensation of tingling of the skin, throughout the body. Burning sensation in different parts of the skin. Eruption of small pimples like miliary scabies. Nettle-rash.

Tetters. Streaks of a reddish brown. Painless ulcers in the extremities of the fingers and of the toes. Fetid ulcers, with burning pains, and discharge of corrosive and bloody pus. Chilblains. Varices. Plexus of the veins, formed by a dilatation of the capillary vessels, with violent hemorrhage, after the slightest injury. Lymphatic swellings, with suppuration and burning pains. Swelling and induration of the glands. Gangrenous spots from lying in bed; old wounds having heated break out again; punctured wounds which won’t heal.

Arsenicum Album for Moles or Nevi

Itching, burning, swellings; oedema, eruption, papular, dry, rough, scaly; worse cold and scratching. Malignant pustules. Ulcers with offensive discharge. Anthrax. Poisoned wounds. Urticaria, with burning and restlessness. Psoriasis. Scirrhous. Icy coldness of body. Epithelioma of the skin. Gangrenous inflammations. Desquamation of the skin of the body. Skin dry as parchment, cold and bluish. Yellowish color of the skin. Shootings, hot itching, and violent burning in the skin. Reddish or bluish spots in the skin. Petechiae. Inflamed spots, as from morbilli, chiefly in the head, face, and neck.

Miliary eruptions, red and white. Conical pimples, whitish or reddish, with burning itching. Nettle-rash. Eruption of painful black pustules. Eruption of itchy pimples, small and tickling. Eruption of small red pimples, which increase and change into gnawing ulcers, covered with a scurf. Vesicular eruptions. Herpes, with vesicles, and violently burning like fish-scales. Skin jaundiced; general anasarca; black blisters. Pustules filled with blood and pus. Tettery spots, covered with phlyctenule and furfur, with burning nocturnal pains.

Ulcers with raised and hard edges, surrounded by a red and shining crown; with the bottoms like lard, or of a blackish-blue color, with burning pains or shooting, principally when the parts affected become cold. Ulcers, hard on the edges, stinging, burning spongy; with proud flesh; turning black; flat; pus thin, ichorous (cancers). Fetid smell, ichorous suppuration, ready bleeding, putridity, and bluish or greenish color of the ulcers. Thin crusts or proud flesh on the ulcers. Spacelus. Want of secretion in the ulcers. Carbuncles (burning). Inflammatory tumors with burning pains. Warts. Ulcers inform of a wart. Chilblains. Varices. Discolored nails.

Anthracinum

This nosode has proven a great remedy in epidemic spleen diseases of domestic animals, and in septic inflammation, carbuncles and malignant ulcers. In boils and boil-like eruptions, acne. Terrible burning. Induration of cellular tissue, abscess, bubo, and all inflammation of connective tissue in which there exists a purulent focus.

Tissues: Hemorrhages, black, thick, tar-like, rapidly decomposing, from any orifice. Glands swollen, cellular tissues edematous and indurated. Septicemia. Ulceration, sloughing and intolerable burning. Erysipelas. Black and blue blisters. Dissecting wounds. Insect stings. Bad effects from inhaling foul odors. Gangrenous parotitis. Succession of boils. Gangrene. Foul secretions.

P. S: This article is only for doctors having good knowledge about Homeopathy and allopathy, for learning purpose(s).

For proper consultation and treatment, please visit our clinic.

None of above-mentioned medicine(s) is/are the full/complete treatment, but just hints for treatment; every patient has his/her own constitutional medicine.

To order medicine by courier, please send your details at WhatsApp– +923119884588

Dr. Sayyad Qaisar Ahmed (MD {Ukraine}, DHMS), Abdominal Surgeries, Oncological surgeries, Gastroenterologist, Specialist Homeopathic Medicines.

  Senior research officer at Dnepropetrovsk state medical academy Ukraine.

Location:  Al-Haytham clinic, Umer Farooq Chowk Risalpur Sadder (0923631023, 03119884588), K.P.K, Pakistan.

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