The main signs and symptoms of Gaucher disease include the following:

• Anemia (low red blood cell count).
• Fatigue (tiredness)
• Low platelet count, that can lead to easy bruising.
• Enlarged spleen and liver (hepatosplenomegaly).
• Enlarged Liver.
• Lung problems.
• Eye movement disorders.
• Yellow spots in the eyes.
• Easy bleeding that is difficult to stop.
• Bone pain, bone crisis (severe bone pain often accompanied by fever), and the chance of easily broken bones.

Signs and symptoms vary among people with Gaucher disease. There are several types of Gaucher disease including type 1, 2, 3 Gaucher disease: perinatal lethal Gaucher disease, and cardiovascular Gaucher disease. The most common type of Gaucher disease is type 1, and this type typically does not affect the nervous system.

Gaucher disease has been referred to in the medical literature by a number of different names. These include:

• Cerebroside lipidosis syndrome
• Gaucher splenomegaly
• Gaucher syndrome
• Gaucher’s disease
• Gaucher’s disease
• GD
• Glucocerebrosidase deficiency
• Glucocerebrosidases
• Glucosyl cerebroside lipidosis
• Glucosyl ceramidase deficiency
• Glucosylceramide beta-glucosidase deficiency
• Glucosylceramide lipidosis
• Kerasin histiocytosis
• Kerasin lipidosis
• Kerasin thesaurismosis
• Lipoid histiocytosis (kerasin type)

Type one of Gaucher disease

Patients with type 1 Gaucher disease usually first notice painless enlargement of the spleen, anemia, or bleeding and bruising due to low platelet count. The enlargement of the spleen may become severe and may limit a child’s growth due to the energy required to sustain the enlarging spleen. An enlarged liver and abnormal liver function tests are also characteristic signs. Skeletal involvement by Gaucher disease is common and can take the form of bone pain, fractures of bone, and a defect of the thigh bone (femur).

Type 2 Gaucher disease (acute neuronopathic form)

This rare type of Gaucher disease affects the nervous system and is termed neuronopathic Gaucher disease. Signs and symptoms include seizures, eye movement problems, and brain damage. Type 2 Gaucher disease is very severe and typically leads to life-threatening medical problems that begin in infancy.

Type 3 Gaucher disease (chronic neuronopathic form)

Like Type 2 Gaucher disease, type 3 Gaucher is a neuronopathic form of Gaucher disease that affects the nervous system, but symptoms do not progress as rapidly as in Type 2. The signs and symptoms may appear in infancy or later in childhood.

Perinatal lethal Gaucher disease

Perinatal lethal Gaucher disease is the most severe form of the condition. With this type, the life-threatening conditions can appear before birth. There may be excessive swelling and fluid accumulation in the fetus (hydrops fetalis) prior to birth. Other features can include severe neurological disturbances, abnormal facial features, hepatosplenomegaly, and dry or scaly skin. Most infants with this form of the condition survive only a few days after birth.

Cardiovascular Gaucher disease

This type of Gaucher disease, considered a rare subgroup of type 3 disease, primarily affects the heart, leading to calcification or hardening of the heart valves. Sometimes, symptoms and signs of other types of Gaucher disease may also be present.

How is Gaucher disease inherited?

Gaucher disease is inherited in an autosomal recessive pattern, meaning that both parents must carry a copy of the defective gene in order for a child to be affected.

How common is Gaucher Disease?

Gaucher disease is most common in people of Ashkenazi Jewish descent, affecting about 1 out of every 855 people.

• In people of Ashkenazi Jewish descent Type 1 Gaucher disease is more common and affects 1 out of every 855 people.
• About 1 out of every 15 people of Ashkenazi Jewish descent are thought to be carriers of the genetic mutation responsible for Gaucher disease.
• The other types of Gaucher disease do not occur more frequently in people of Ashkenazi Jewish heritage.
• In the non-Jewish population, Gaucher disease affects 1 out of every 40,000 people.

Those with family members affected with Gaucher disease may want to consider genetic counseling and screening for the genetic mutation.

Types of Genetic Disorders

There are a number of types of genetic inheritance and associated disorders. For example, single gene or monogenetic inheritance disorders include:

• Iron overload (hemochromatosis)
• Sickle cell anemia
• Marfan syndrome
• Huntington’s disease
• Cystic fibrosis

Another type of genetic inheritance is multifactorial inheritance disorders, for example:

• Diabetes
• Cancer
• Alzheimer’s disease

All of the types of Gaucher disease are caused by a deficiency of the enzyme glucocerebrosidase, leading to an abnormal buildup of fatty substances, glycolipids, in the body cells. Mutations in the gene known as GBA1 are the cause of the deficient enzyme, and over 300 different GBA1 mutations have been identified in people with Gaucher disease. The mutations are inherited (passed from parent to offspring) in an autosomal recessive manner.

• The four most common mutations of the GBA1 gene are N370S, L444P, 84gg, and IVS2[+1].
• DNA analysis for these 4 mutations can detect 90%-95% of the mutations associated with Gaucher Disease in the Ashkenazi Jewish population, and 50%-75% of the associated mutations in the general population.

A blood test is used to make the diagnosis of Gaucher disease.

• The enzyme assay test measures the activity of the glucocerebrosidase enzyme in certain white blood cells. Having less than 15% of normal enzyme activity is diagnostic for Gaucher disease.
• Genetic analysis is also done to establish the specific type of mutations in the GBA1 gene.

There is no cure for Gaucher disease in allopathy, but medical treatments are available.

Enzyme replacement therapy (ERT) is the primary form of treatment for people with type 1 and Gaucher disease and for the non-neurologic symptoms of type 3 Gaucher disease.

The drug is given intravenously, generally at 2-week intervals. There are three ERT drugs available, imiglucerase (Cerezyme), velaglucerase alfa (VPRIV), and taliglucerase alfa (Elelyso).

Other medications available to treat Gaucher disease include drugs that block the production of the sphingolipids that accumulate in cells and cause symptoms. These drugs are known as glucosylceramide synthase inhibitors and are taken by mouth. Two drugs in this class are migalastat (Zavesca) and eliglustat (Cerdelga).

Formerly, the condition was often treated by surgical removal of the spleen (splenectomy). However, this is typically not necessary given the availability of ERT.

• The prognosis for people with type 1 or type 3 Gaucher disease who receive Homeopathic treatment is very good.
• Many people with Gaucher disease have few symptoms and can expect a normal lifespan even without treatment.
• One study estimated life expectancy at birth for people with type 1 Gaucher disease to be 68 years, compared with 77 years in the general population.
• Type 2 Gaucher disease usually results in death within the first few years of life.

Homeopathic Treatment of Gaucher’s Disease

Arsenicum Album

A profoundly acting remedy on every organ and tissue. Debility, exhaustion, and restlessness, with nightly aggravation, irritable weakness. Great thirst; drinks much, but little at a time. Nausea, retching, vomiting, after eating or drinking. Anxiety in pit of stomach. Burning pain. Heartburn, long-lasting eructation. Vomiting of blood, bile, green mucus, or brown-black mixed with blood. Stomach extremely irritable; seems raw, as if torn. Gastralgia from slightest food or drink. Dyspepsia from vinegar, acids, ice-cream, ice-water, tobacco.

Terrible fear and dyspnea, with gastralgia; also, faintness, icy coldness, great exhaustion. Malignant symptoms. Everything swallowed seems to lodge in the esophagus, which seems as if closed and nothing would pass. Ill effects of vegetable diet, melons, and watery fruits generally. Craves milk. Unable to lie down, fears suffocation.

Bradycardia, Tachycardia, pain, dyspnea, faintness. Irritable heart. Pulse more rapid in morning. Dilatation. Cyanosis. Fatty degeneration. Angina pectoris.

Extremities: Trembling, twitching, spasms, weakness, heaviness, uneasiness. Cramps in calves. Swelling of feet.

Abdomen: Gnawing, burning pains like coals of fire; relieved by heat. Liver and spleen enlarged and painful. Ascites and anasarca. Abdomen swollen and painful. Pain as from a wound in abdomen on coughing.

Skin: Itching, burning, swellings; oedema, eruption, papule, dry, rough, scaly; worse cold and scratching. Malignant pustules. Ulcers with offensive discharge. Poisoned wounds. Urticaria, with burning and restlessness. Psoriasis. Scirrhous. Icy coldness of body. Epithelioma of the skin. Gangrenous inflammations.

Rectum: Painful, spasmodic protrusion of rectum. Tenesmus. Burning pain and pressure in rectum and anus.

Stool: Small, offensive, dark, with much prostration. Worse at night, and after eating and drinking; from chilling stomach, alcoholic abuse, spoiled meat. Dysentery dark, bloody, very offensive. Cholera, with intense agony, prostration, and burning thirst. Body cold as ice. Hemorrhoids burn like fire, relieved by heat. Skin excoriated about anus.

Urine: Scanty, burning, involuntary. Bladder as if paralyzed. Albuminous. Epithelial cells; cylindrical clots of fibrin and globules of pus and blood. After urinating, feeling of weakness in abdomen. Bright’s disease. Diabetes.

Fever: High temperature. Periodicity marked with adynamic. Septic fevers. Intermittent. Paroxysms incomplete, with marked exhaustion. Hay-fever. Cold sweats. Typhoid, not too early. Complete exhaustion. Delirium; worse after midnight. Great restlessness.

Natrum Muriaticum

Dropsies and oedemas, anemia, leukocytosis, intermittent fever, anemia, chlorosis, many disturbances of the alimentary tract and skin. Great debility: most weakness felt in the morning in bed. Coldness. Emaciation most notable in neck. Great liability to take cold. Dry mucous membranes. Constrictive sensation throughout the body. Great weakness and weariness. Oversensitive to all sorts of influences. Hyperthyroidism. Goiter. Addison’s disease. Diabetes.

Hungry, yet loose flesh. Heartburn, with palpitation. Unquenchable thirst. Sweats while eating. Craving for salt. Aversion to bread, to anything slimy. Throbbing in pit. Sticking sensation in cardiac orifice. Cutting pain in abdomen. Distended. Pain in abdominal ring on coughing.

Rectum: Burning pains and stitching after stool. Anus contracted, torn, bleeding. Constipation: stool dry, crumbling (Am m; Mag m). Painless and copious diarrhea, preceded by pinching pain in abdomen.

Urine: Pain just after urinating (Sars). Increased, involuntary when walking, coughing, etc. Has to wait a long time for it to pass if others are present.

Tachycardia. Sensation of coldness of heart. Heart and chest feel constricted. Fluttering, palpitating; intermittent pulse. Heart’s pulsations shake body. Intermits on lying down.

Extremities: Pain in back, with desire for some firm support. Every movement accelerates the circulation. Palms hot and perspiring. Arms and legs, but especially knees, feel weak. Hangnails. Dryness and cracking about fingernails. Numbness and tingling in fingers and lower extremities. Ankles weak and turn easily. Painful contraction of hamstrings. Cracking in joints on motion. Coldness of legs with congestion to head, chest, and stomach.

Sleep: Sleepy in forenoon. Nervous jerking during sleep. Bad dreams.

Skin: Greasy, oily, especially on hairy parts. Dry eruptions, especially on margin of hairy scalp and bends of joints. Fever blisters. Urticaria; itch and burn. Crusty eruptions in bends of limbs, margin of scalp, behind ears. Warts on palms of hands. Eczema; raw, red, and inflamed; worse, eating salt, at seashore. Affects hair follicles. Alopecia. Hives, itching after exertion. Greasy skin.

Fever: Chill in morning. Heat: violent thirst, increases with fever. Fever-blisters. Coldness of the body, and continued chilliness very marked. Hydremic in chronic malarial states with weakness, constipation, loss of appetite, etc. Sweats on every exertion.

Nux vomica

Bruised soreness of abdominal walls. Flatulent distension, with spasmodic colic. Colic from uncovering. Liver engorged, with stitches and soreness. Colic, with upward pressure, causing short breath, and desire for stool. Sour taste, and nausea in the morning, after eating. Weight and pain in stomach; worse, eating, Sour, bitter eructation. Nausea and vomiting.

Constipation, with frequent ineffectual urging, incomplete and unsatisfactory; feeling as if part remained un expelled. Alternate constipation and diarrhea-after abuse of purgatives. Urging to stool felt throughout abdomen. Itching, blind hemorrhoids, with ineffectual urging to stool; very painful; after drastic drugs. Diarrhea after a debauch; worse, morning. Frequent small evacuations. Scanty stool, with much urging. Dysentery: stools relieve pains for a time. Constant uneasiness in rectum. Diarrhea, with jaundice.

Skin: Body burning hot, especially face; yet cannot move or uncover without feeling chilly. Urticaria, with gastric derangement. Acne; skin red and blotchy.

Fever: Cold stage predominates. Paroxysms anticipate in morning. Excessive rigor, with blueness of fingernails. Aching in limbs and back, and gastric symptoms. Chilly; must be covered in every stage of fever. Perspiration sour; only one side of body. Chilliness on being uncovered, yet he does not allow being covered. Dry heat of the body.

Conium Maculatum

Debility, hypochondriasis, urinary troubles, tumors, trembling, and palpitation. Cancerous diathesis. Arterio-sclerosis. Caries of sternum. Enlarged glands.

Soreness about the root of tongue. Terrible nausea, acrid heartburn and acid eructation; worse on going to bed. Painful spasms of the stomach. Amelioration from eating and aggravation a few hours after meals; acidity and burning; painful spot the level of the sternum.

Abdomen: Severe aching in and around the liver. Chronic jaundice, and pains in right hypochondrium. Sensitive, bruised, swollen, knife-like pains. Painful tightness.

Stool: Frequent urging; hard, with tenesmus. Tremulous weakness after every stool. Heat and burning in rectum during stool.

Urine: Much difficulty in voiding. It flows and stops again. Interrupted discharge. Dribbling in old men.

Respiratory: Dry cough, almost continuous, hacking; worse, evening and at night; caused by dry spot in larynx with itching in chest and throat, when lying down, talking or laughing, and during pregnancy. Oppressed breathing, constriction of chest; pains in chest. Dorsal pain between shoulders. Dull aching in lumbar and sacral region.

Trembling extremities especially lower, Muscular weakness, putting feet on chair relieves pain.

Skin: Axillary glands pain, with numb feeling down arm. Induration after contusions. Yellow skin, with popular eruption; yellow fingernails. Glands enlarged and indurated, also mesenteric. Flying stitches through the glands. Tumors, piercing pains; worse, at night. Chronic ulcers with fetid discharge. Sweat as soon as one sleeps, or even when closing eyes. Night and morning sweat, with offensive odor, and smarting in skin.

Ferrum Metalicum

Best adapted to young weakly persons, anemic and chlorotic, with pseudo-plethora, who flush easily; cold extremities; over sensitiveness; worse after any active effort. Weakness from mere speaking or walking though looking strong. Pallor of skin, mucous membranes, face, alternating with flushes. Pseudo-plethora. Muscles flabby and relaxed. Chest oppressed, breathing difficult.

Voracious appetite, or absolute loss of appetite. Loathing of sour things. Attempts to eat bring on diarrhea. Spits up food by the mouthful. Eructation of food after eating, without nausea. Nausea and vomiting after eating. Vomiting immediately after eating. Vomiting after midnight. Intolerance of eggs. Distention and pressure in the stomach after eating. Heat and burning in stomach. Soreness of abdominal walls. Flatulent dyspepsia.

Heart: Palpitation; worse, movement. Sense of oppression. Anemic murmur. Pulse full, but soft and yielding; also, small and weak. Heart suddenly bleeds into the blood vessels, and as suddenly draws a reflux, leaving pallor of surface.

Skin: Pale; flushes readily; pits on pressure. General coldness of extremities; head and face hot.

Stool: Undigested, at night, while eating or drinking, painless. Ineffectual urging: stool hard, followed by backaches or cramping pain in rectum; prolapsus recti; itching of anus, especially young children.

Urine: Involuntary; worse daytime. Tickling in urethra extending to bladder.

Phosphorus

Phosphorus is a destructive metabolism. Causes yellow atrophy of the liver and sub-acute hepatitis, jaundice in patients with Cirrhosis of Liver, stool very offensive, vomiting of blood, desire for cold drinks, juices and ice creams.

Hunger soon after eating. Sour taste and sour eructation after every meal. Belching large quantities of wind, after eating. Throws up ingesta by the mouthfuls. Vomiting: water is thrown up as soon as it gets warm in the stomach. Postoperative vomiting. Cardiac opening seems contracted, too narrow; the food scarcely swallowed, comes up again. Pain in stomach; relieved by cold food, ices. Region of stomach painful to touch, or on walking. Inflammation of stomach, with burning extending to throat and bowels. Bad effects of eating too much salt.

Abdomen feels cold. Sharp, cutting pains. A very weak, empty, gone sensation felt in whole abdominal cavity. Liver congested. Acute hepatitis. Fatty degeneration. Jaundice. Pancreatic disease. Large, yellow spots on abdomen.

Stool: Very fetid stools and flatus. Long, narrow, hard, like a dog’s and difficult to expel. Desire for stool on lying especially on left side. Painless, copious debilitating diarrhea. Green mucus with grains like sago. Involuntary; seems as if anus remained open. Great weakness after stool. Discharge of blood from rectum, during stool. White, hard stools. Bleeding hemorrhoids.

Urine: Hematuria, especially in acute Bright’s disease. Turbid, brown, with red sediment.

Acid Sulphuricum

Heartburn; sour eructation; sets teeth on edge, Water causes coldness of stomach, Sour vomiting. Desire for fresh food. Hiccough. Coldness of stomach relieved by applied heat Nausea with chilliness, Weak feeling, with dragging into the hips and small of back. Feeling as if hernia would protrude, especially left side (increased pressure).

Piles; oozing dampness. Rectum feels as if it had a big ball. Diarrhea, fetid, black, with sour odor of body, and empty faint feeling in abdomen.

Female: Menstruation early and profuse. Erosion of cervix in the aged; easily bleeding. Acrid, burning leucorrhea, often of bloody mucus.

Bad effects from mechanical injuries, with bruises and livid skin. Ecchymosis. Petechiae. Purpura hemorrhagic. Livid, red, itching blotches. Hemorrhage of black blood from all outlets. Cicatrices turn red and blue and become painful. Chilblains with gangrenous tendency. Carbuncles, boils and other staphylococcus and streptococcus infections.

Carbolicum Acidum

Stomach pains are terrible; come and go suddenly. Physical exertion brings on abscess. Putrid discharges. Scarlet fever, with marked tendency to destruction of tissue internally, and fetid odor. Spasmodic coughs. Arthritis. Constant belching, nausea, vomiting, dark olive green. Heat rises up esophagus. Flatulent distention of stomach and abdomen. Painful flatulence, low apatite, Fermentative dyspepsia with bad taste and breath. Puerperal fever, with offensive vaginal discharge. Irritating leucorrhea, causing itching and burning. Itching vesicles, with burning pain. Burns tend to ulcerate.

Constipation, with very offensive breath. Bloody, like scrapings of intestines. Great tenesmus. Diarrhea; stools thin, black, putrid.

Urine: Almost black. Diabetes. Irritable bladder in old men with frequent urination at night, of probable prostatic nature.

Ferrum Arsenic0sum

Enlarged liver and spleen, with fever (Enlarged spleen with high fever of a continued type), albuminuria. Simple and pernicious anemia and chlorosis, pale, jaundiced, emaciated; abdomen filled with enlarged and indurated liver and spleen, slightly tender to pressure. Skin dry. Eczema, psoriasis, impetigo.

Constipation, or, sometimes, colliquative diarrhea, the stools consisting of undigested matter and mucus, no thirst during any stage of the fever; heat intense and prolonged with slight burning of the whole body, emaciation, and debility.

Ferrum Iodatum

Scrofulous affections, glandular enlargements, and tumors call for this remedy. Crops of boils. Acute nephritis following eruptive diseases. Uterine displacements. Body emaciated Anemia Exophthalmic goiter following suppression of menses. Debility following drain upon vital forces. Impetigo of the cheek.

Stomach: Food seems to push up into throat, as if it had not been swallowed.

Abdomen: Fullness, even after a little food; stuffed feeling, as if she could not lean forward.

Throat: Sore, as if of a splinter, shooting in different directions. Hoarse.

Respiratory: Coryza; discharge of mucus from nose, trachea, and larynx. Pressure beneath sternum. Scrofulous swelling of nose. Chest feels oppressed. Hemoptysis.

Urinary: Urine dark. Sweet smelling. Crawling sensation in urethra and rectum. Sensation as if urine were stopped at fossa navicularis. Difficulty in retaining urine. Incontinence in anemic children.

Female: On sitting, feeling as if something pressed upward in vagina. Much bearing down. Retroversion and prolapse of uterus. Leucorrhea like boiled starch. Manses suppressed or scanty. Itching and soreness of vulva and vagina.

Urtica Urens

Profuse discharge from mucous surfaces. Enuresis and urticaria. Spleen affections. Antidotes ill-effects of eating shellfish. Symptoms return at the same time every year. Gout and uric acid diathesis. Favors elimination. A remedy for agalactia and lithiasis.

Rheumatism associated with urticaria-like eruptions. Neuritis.

Head: Vertigo, headache with spleen pains.

Abdomen: Diarrhea chronic disease of large intestine characterized by large secretion of mucus.

Male: Itching of scrotum, keeps him awake; scrotum swollen.

Female: Diminished secretion of milk. Uterine hemorrhage. Acid and excoriating leucorrhea. Pruritus vulvae, with stinging, itching, and oedema. Arrests flow of milk after weaning. Excessive swelling of breasts.

Extremities: Pain in acute gout deltoid; pain in ankles, wrists.

Skin: Itching blotches. Urticaria, burning heat, with formication; violent itching. Consequences of suppressed nettle rash. Rheumatism alternates with nettle-rash. Burn confined to skin. Urticaria nodosa. Erythema, with burning and stinging. Burns and scalds. Chickenpox. Angioneurotic oedema. Herpes labialis with sensation of heat and itching. Itching and stinging of scrotum.

Fever: General heat in bed with soreness over abdomen. Fever of gout. Tropical fever.

Cardus Marianus

The action of Cardus Marianus is centered in the liver, and portal system, causing soreness, pain, jaundice. Has specific relation to the vascular system. Abuse of alcoholic beverages, especially beer. Varicose veins and ulcers. Diseases of miners, associated with asthma. Dropsical conditions depending on liver disease, and when due to pelvic congestion and hepatic disease. Disturbs sugar metabolism. Influenza when liver is affected. Debility. Hemorrhages, especially connected with hepatic disease, dropsical accumulation of water in abdomen (ascites).

The next field is bleeding consequent to liver damage, liver pain and sensitiveness, feel fatigued or tired and have bouts of nausea and vomiting due to Liver Cirrhosis. Taste bitter. Aversion to salt meat. Appetite small; tongue furred; nausea; retching; vomiting of green, acid fluid. Stitches in left side of stomach, near spleen. Gallstone disease with enlarged liver.

Pain in region of liver. Left lobe very sensitive. Fullness and soreness, with moist skin. Constipation; stools hard, difficult, knotty; alternates with diarrhea. Stools bright yellow. Swelling of gallbladder with painful tenderness. Hyperemia of liver, with jaundice. Cirrhosis, with dropsy.

Rectum: Hemorrhagic piles, prolapse or rectum, burning pain in anus and rectum, hard and knotting, clayey stools. Profuse diarrhea due to rectal cancer. 10 drops doses.

Urine: Cloudy; golden-colored.

Skin: Itching on lying down at night. Varicose ulcers. Eruption on lower part of sternum.

Extremities: Pain in hip-joint, spreading through buttocks and down thigh; worse from stooping. Difficult rising. Weakness felt in feet, especially after sitting.

Chelidonium Majus

A prominent liver remedy, jaundice, pain under right scapula, Jaundice due to hepatic and gallbladder obstruction. Gall-colic. Distention. Fermentation and sluggish bowels. Constriction across, as by a string. Liver enlarged. Gallstones. Tongue yellow, with imprint of teeth; large and flabby. Taste bitter, pasty. Bad odor from mouth.

Constipation; stools hard, round balls, like sheep’s dung, bright yellow, pasty; clay-colored, stools float in water; alternation of diarrhea and constipation. Burning and itching of anus.

Urine: Profuse, foaming, yellow urine, like beer dark, turbid.

Pain in arms, shoulders, hands, tips of fingers. Icy coldness of tips of fingers; wrists sore, tearing in metacarpal bones. Whole flesh sore to touch. Rheumatic pain in hips and thighs; intolerable pains in heels.

Skin: Dry heat of skin; itches, yellow. Painful red pimples and pustules. Old, spreading, offensive ulcers. Wilted skin. Sallow, cold, clammy.

Calceria Carbonica

The keynote of its action, the glands, skin, and bones, being instrumental in the changes wrought. Increased local and general perspiration, swelling of glands, scrofulous and rachitic conditions. It covers the tickling cough, fleeting chest pains, nausea, acidity and dislike of fat. Gets out of breath easily.

Aversion to meat, boiled things; craving for indigestible things-chalk, coal, pencils; also, for eggs, salt and sweets. Milk disagrees. Frequent sour eructation; sour vomiting. Dislike of fat. Loss of appetite when overworked. Heartburn and loud belching. Cramps in stomach; worse, pressure, cold water. Ravenous hunger. Swelling over pit of stomach, like a saucer turned bottom up. Repugnance to hot food. Pain in epigastric region to touch. Thirst; longing for cold drinks. Aggravation while eating. Hyperchlorhydria (Phos).

Abdomen: Sensitive to slightest pressure. Liver region painful when stooping. Cutting in abdomen; swollen abdomen. Incarcerated flatulence. Inguinal and mesenteric glands swollen and painful. Cannot bear tight clothing around the waist. Distention with hardness. Gall-stone colic. Enlarged Spleen (Splenomegaly). Increase of fat in abdomen. Umbilical hernia. Trembling; weakness, as if sprained. Children are late in learning to walk.

Stool: Crawling and constriction in rectum. Stool large and hard; whitish, watery, sour. Prolapse ani, and burning, stinging hemorrhoids. Diarrhea of undigested, food, fetid, with ravenous appetite. Children’s diarrhea. Constipation; stool at first hard, then pasty, then liquid.

Urine: Dark, brown, sour, fetid, abundant, with white sediment, bloody. Irritable bladder. Enuresis

Cutting pains in uterus during menstruation. Manses too early, too profuse, too long, with vertigo, toothache and cold, damp feet. Palpitation at night and after eating. Palpitation with feeling of coldness, with restless oppression of chest; after suppressed eruption. Pain as if sprained; can scarcely rise.

Chill at 2 pm begins internally in stomach region. Fever with sweat. Pulse full and frequent. Chilliness and heat. Partial sweats. Night sweats, especially on head, neck and chest. Hectic fever. Heat at night during menstruation, with restless sleep.

Skin: Unhealthy; readily ulcerating; flaccid. Small wounds do not heal readily. Glands swollen. Nettle rash; better in cold air. Warts on face and hands. Petechial eruptions. Chilblains. Boils.

Iodum

All glandular structures, respiratory organs, circulatory system are especially affected. Abnormal Vaso-constriction, capillary congestion followed by oedema, ecchymosis, hemorrhages, and nutritive disturbances.

Throbbing at pit of stomach. Ravenous hunger and much thirst. Empty eructation, as if every particle of food were turned into gas. Anxious and worried if he does not eat. Loss flesh, yet hungry and eating well.

Abdomen: Liver and spleen sore and enlarged, Enlarged Spleen (Splenomegaly). Jaundice. Mesenteric glands enlarged. Pancreatic disease. Cutting pain in abdomen.

Stool: Hemorrhage at every stool. Diarrhea, whitish, frothy, fatty. Constipation, with ineffectual urging; better by drinking cold milk. Constipation alternating with diarrhea.

Urine: Frequent and copious, dark yellow green, thick, acrid with cuticle on surface.

Menstruation irregular. Uterine hemorrhage. Skin hot, dry, yellow and withered. Glands enlarged. Nodosities. Anasarca of cardiac disease. Flushes of heat all over body. Marked fever, restlessness, red cheeks, apathetic. Profuse sweat.

Capsicum

Burning in tip of tongue. Atonic dyspepsia. Much flatulence, especially in debilitated subjects. Intense craving for stimulants. Vomiting, sinking at pit of stomach. Much thirst; but drinking causes shuddering. Enlarged Spleen (Splenomegaly).

Stool: Bloody mucus, with burning and tenesmus; drawing pain in back after stool. Thirsty after stool, with shivering. Bleeding piles, with soreness of anus. Stinging pain during stool.

Urine: Strangury, frequent, almost ineffectual urging. Burning in orifice. Comes first in drops, then in spurts; neck of bladder spasmodically contracted. Ectropion of meatus. Uterine hemorrhage near the menopause, with nausea. Sticking sensation in left ovarian region. Coldness, with ill-humor. Shivering after drinking. Chill begins in back; better, heat. Must have something hot to back. Thirst before chill.

Ceanothus Americanus

Best medicine for the spleen. Enlarged Spleen (Splenomegaly). Ague cake of malaria. A left-sided remedy generally. Anemic patients where liver and spleen are at fault. Diarrhea and dysentery. Heart, disordered. Intermittent fever. Jaundice. Marked blood pressure, reducing powers. Active hemostatic, materially reducing the clotting of blood, palpitation and dyspnea on exertion along with splenomegaly. Insomnia, nightmares. Intermittent fever with splenic enlargements. Cheeks and ears hot, with cold fingers, pulse 120; throbbing carotid arteries.

Congested feelings in lungs, Palpitation and dyspnea, with enlarged spleen. Pulse full and very strong, heart’s pulsations visible through the clothes. Heartbeat so hard it shook him all over. Chest feels too small for heart.

Abdomen: Enlarged Spleen (Splenomegaly). Splenitis; pain all up the left side, deep-seated pain in left hypochondrium; pain and fullness in left side; cutting pain. Pain, inflammation, enlargement of spleen, deep-seated pain in left hypochondrium, hypertrophy of spleen. Leukemia. Violent dyspnea. Manses profuse, and yellow weakening leucorrhea. Unable to lie on left side. Pain in liver and back.

Stool and Rectum. Diarrhea. Dysentery. Stool light brown, with loud flatus. Continual bearing down in rectum with constricting sensation.

Urine: Constant urging to urinate. Green; frothy; contains bile, sugar.

Quercus Robur

Quercus Robur (Var.Pedunculata and sessilifera)/Oak. N. O (genus Quercus)/Corylaceae or Cupuliferae. Tincture of acorns (peeled and crushed or shredded). Spirit distilled from the tincture is called “Spiritus glandium quercus”. Water extract of acorns with addition of alcohol is called “Aqua glandium quercus”.

Clinical symptoms: Alcoholism. Breath, offensive. Constipation. Diarrhea. Dropsy (splenic). Fistula. Giddiness. Gout. Intermittent fever. Leucocythaemia splenica. Spleen affections, ascites and dropsy of lower extremities, intermittent fevers, gnawing at pit of stomach. Flatulent dyspepsia, diarrhea, polyuria, Fluttering and irregular heart (Bradycardia). Gouty eczema. Dropsy. Tottering gait. Varicose veins.

China Officanalis

Hectic fever, Intermittent fever, Hectic fever, Traumatic fever, Jaundice, Liver, diseases of; cirrhosis of. Meniere’s disease, Psoriasis, Spleen affections, enlarged Spleen (Splenomegaly), Gall-stone colic. Alcoholism. Amblyopia. Anemia. Aphthae. Apoplexy Appetite, disordered. Asthma. Back, weakness of. Bilious attack. Catarrhal affections. Coma. Constipation. Cough. Debility. Delirium. Diarrhea. Dropsy. Dyspepsia. Liver diseases; Liver cirrhosis, Varicose veins.

Cough. Debility. Delirium. Diarrhea. Dropsy. Dyspepsia. Ears, deafness; noises in. Emissions. Empyema. Erysipelas. Facial neuralgia. Hemorrhages. Hemorrhoids. Headache. Hip-joint pain.

Iodium

Diarrhea. Enteric fever. Jaundice, liver diseases. Lymphatic swellings. Enlarged Spleen (Splenomegaly). saponaceous, sourish, or bitter salt taste. Increased thirst day and night. Appetite variable; at one time balmy, at another, absence of appetite. Unusual hunger, with amelioration after a meal (after having eaten a good deal). Great weakness of digestion. Eats too often and too much; rapid digestion but losing flesh all the time. Difficulty of respiration, and dyspnea. Difficulty of expanding the chest on taking an inspiration. Violent palpitation of the heart, Hypertrophy of heart, Fatty degeneration of heart, Pulse rapid, small, weak, with tumultuous, irregular, at times intermittent action of heart. Dropsical swelling.

Hemorrhage from different organs, Ebullition of blood, and pulsation over the whole body, Great weakness. Skin rough, dry, or clammy, moist, and of a dirty yellow. Tetters. Furfur. Panaras. Itching and itching pimples on an old cicatrix. Populous eruptions tending to pustulation.

Shivering, even in a warm room. Chill alternating with heat. Cold feet all night. Internal dry heat, with external coldness. Profuse night-sweat. Increase of bodily heat. Fugitive heat. Acid perspiration in the morning. Pulse quick, small, and hard; weak, threadlike. The pulse becomes much quicker as soon as one moves about. Fever, with consumption.

Stomach: Risings, generally acid, with burning sensation. Heartburn, after heavy food. Hiccough. Pyrosis, especially after indigestible food. Qualmishness, nausea (with spasmodic pain in the stomach). Frequent nausea. Violent vomiting renewed by eating. Vomiting of bilious matter, or of yellowish mucus. Excessive pains in the stomach, with bilious evacuations. Aching in the stomach after every meal. Cramp-like, gnawing, or burning pains in the stomach. Inflammation in the stomach. Pulsations in the epigastrium. Gastric derangement with constipation.

Abdominal pains, which return after every meal. Inflation of the abdomen. Incarceration of flatulence (left side of abdomen). Enlargement of the abdomen, which renders it impossible to lie down without danger of suffocation. Region of liver sore to pressure; swelling and hypertrophy of liver; jaundice. Hard, painful swelling of the spleen. Cramp-like pains in the abdomen. Violent colic. Pains in the abdomen, like those of parturition. Swelling and inflammation of the mesenteric glands. Pancreas enlarged; whitish, whey-like diarrhea. Abdominal pulsations; throbbing of abdominal aorta. Trembling in the abdomen, from the pit of the stomach to the periphery, with increased heat. Hard swelling of the inguinal glands.

Hard, knotty, dark-colored feces. Constipation. Loose, soft evacuations, sometimes whitish, alternately with constipation. Evacuations copious of the consistency of pap. Violent, frothy diarrhea, or composed of sanguineous mucus. Dysenteric evacuations of thick mucus, or sometimes purulent, with retention of fecal matter. In the evening, sensation of itching and burning in the anus. Piles protrude and burning.

Urinary Organs. Suppressed secretion of urine. Copious and frequent flow of urine. Involuntary emission of urine at night. Urine of a deep color, turbid, or yellowish green; or milky; or acrid and corrosive. Parti-colored cuticle on the urine. (Incontinence in old people with prostatic enlargement). Diabetes.

Bryonia Alba

Alcoholism. Amenorrhea. Anger, effects of. Aphthae. Apoplexy. Asthma. Bilious attack. Brain, affections of. Breast, inflamed. Bronchitis. Cancer. Chill, effects of. Chlorosis. Constipation. Consumption. Diarrhea. Dropsy. Dyspepsia. Eczema. Enteric fever. Eruptions. Gastroenteritis. Hemorrhages. Hands, swollen. Headache. Heart inflammation. Intermittent fevers. Jaundice. Liver diseases. Lumbago. Measles. Meningitis. Menstruation, vicarious. Miliaria. Puerperal fever. Pyuria. Relapsing fever. Remittent fever.

Loss of appetite. Taste insipid, clammy, putrid. Insipidity of food. Sweetish taste. Bitter taste of all food, or only after mealtime, or at other times, as well as in the morning. Burning thirst, sometimes after a meal, increased by taking beer. Infrequent, but copious, drinking. Empty risings. Regurgitation if the food after every meal. Hiccough. Nausea and inclination to vomit, especially after eating food or on rising after lying down. Nausea, with inclination to vomit and anxiety, when sitting, or on forcing oneself to drink, Contractive pains in the stomach sensible to the touch, or on coughing.

Pains in the liver, mostly shooting, tensive, or burning, especially on being touched, on breathing, or on coughing. Tractive pains in the hypochondrium, extending to the stomach and the back, in the morning and after dinner.

Hard swelling in the hypochondriac and umbilical regions. Shootings in the region of the spleen. Colic with tension of the abdomen, and water brash. Inflation of the abdomen, with pressure in the epigastrium, especially after dinner. Inflammation of the liver. Tearing in the stomach, from the hips to the pit of the stomach. Dropsical swelling of the abdomen. Gurgling and borborygmi in the abdomen, with escape of flatus.

Respiration difficult, or short, rapid, and anxious, or sighing, Constant occasion to make a deep inspiration. Fit of dyspnea. Tension in the chest. Bradycardia (carditis). Frequent sharp pain, stitching in cardiac region, Pulse full and hard, tense, and quick. Swelling of the feet, with redness and heat. Yellow color of the skin. Skin moist and clammy. Burning and pricking over the whole body, as if from nettles, after slight emotions. Erysipelatous inflammation.

Constipation. Feces too large, with difficult evacuation, Diarrhea, with colic, sometimes alternating with constipation and gastralgia. Loose evacuations, of a putrid smell, as of rotten cheese. Diarrhea preceded by pain in the abdomen. Nocturnal diarrhea, with burning pain in the anus. Colliquative diarrhea. Constrictive colic.

Urine scanty, reddish, brownish, and hot. White or may be dark colored, turbid urine, polyuria, Urgent inclination.

Cholesterinum

Cancer of the liver. Obstinate hepatic engorgements. Burning pain inside; on walking holds his hand on side, hurts him so. Opacities of the vitreous. Jaundice; gallstones.

Cholestenone is the physiological opponent of Lecithin. Both seem to play role in the growth of tumors. Gallstones and insomnia.

P. S: This article is only for doctors having good knowledge about Homeopathy and allopathy, for learning purpose(s).

For proper consultation and treatment, please visit our clinic.

None of above-mentioned medicine(s) is/are the full/complete treatment, but just hints for treatment; every patient has his/her own constitutional medicine.

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Dr. Sayyad Qaisar Ahmed (MD {Ukraine}, DHMS), Abdominal Surgeries, Oncological surgeries, Gastroenterologist, Specialist Homeopathic Medicines.

  Senior research officer at Dnepropetrovsk state medical academy Ukraine.

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